APPlications of amyloid-β precursor protein metabolites in macrocephaly and autism spectrum disorder

Metabolites of the Amyloid-β precursor protein (APP) proteolysis may underlie brain overgrowth in Autism Spectrum Disorder (ASD). We have found elevated APP metabolites (total APP, secreted (s) APPα, and α-secretase adamalysins in the plasma and brain tissue of children with ASD). In this review, we...

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Detalles Bibliográficos
Autores principales: Sokol, Deborah K., Lahiri, Debomoy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548831/
https://www.ncbi.nlm.nih.gov/pubmed/37799731
http://dx.doi.org/10.3389/fnmol.2023.1201744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548831/
https://www.ncbi.nlm.nih.gov/pubmed/37799731
http://dx.doi.org/10.3389/fnmol.2023.1201744

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