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The life and times of endogenous opioid peptides: Updated understanding of synthesis, spatiotemporal dynamics, and the clinical impact in alcohol use disorder

The opioid G-protein coupled receptors (GPCRs) strongly modulate many of the central nervous system structures that contribute to neurological and psychiatric disorders including pain, major depressive disorder, and substance use disorders. To better treat these and related diseases, it is essential...

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Detalles Bibliográficos
Autores principales: Margolis, Elyssa B., Moulton, Madelyn G., Lambeth, Philip S., O’Meara, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548835/
https://www.ncbi.nlm.nih.gov/pubmed/36516892
http://dx.doi.org/10.1016/j.neuropharm.2022.109376