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Deciphering the mitophagy receptor network identifies a crucial role for OPTN (optineurin) in acute myeloid leukemia

The selective autophagic degradation of mitochondria via mitophagy is essential for preserving mitochondrial homeostasis and, thereby, disease maintenance and progression in acute myeloid leukemia (AML). Mitophagy is orchestrated by a variety of mitophagy receptors whose interplay is not well unders...

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Detalles Bibliográficos
Autores principales: Meyer, Laura M., Koschade, Sebastian E., Vischedyk, Jonas B., Thoelken, Marlyn, Gubas, Andrea, Wegner, Martin, Basoglu, Marion, Knapp, Stefan, Kaulich, Manuel, Eimer, Stefan, Shaid, Shabnam, Brandts, Christian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549194/
https://www.ncbi.nlm.nih.gov/pubmed/37439113
http://dx.doi.org/10.1080/15548627.2023.2230839