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Deciphering the mitophagy receptor network identifies a crucial role for OPTN (optineurin) in acute myeloid leukemia
The selective autophagic degradation of mitochondria via mitophagy is essential for preserving mitochondrial homeostasis and, thereby, disease maintenance and progression in acute myeloid leukemia (AML). Mitophagy is orchestrated by a variety of mitophagy receptors whose interplay is not well unders...
Autores principales: | Meyer, Laura M., Koschade, Sebastian E., Vischedyk, Jonas B., Thoelken, Marlyn, Gubas, Andrea, Wegner, Martin, Basoglu, Marion, Knapp, Stefan, Kaulich, Manuel, Eimer, Stefan, Shaid, Shabnam, Brandts, Christian H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549194/ https://www.ncbi.nlm.nih.gov/pubmed/37439113 http://dx.doi.org/10.1080/15548627.2023.2230839 |
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