Inhibition of PRMT1 alleviates sepsis‐induced acute kidney injury in mice by blocking the TGF‐β1 and IL‐6 trans‐signaling pathways

Sepsis‐induced acute kidney injury (SI‐AKI) causes renal dysfunction and has a high mortality rate. Protein arginine methyltransferase‐1 (PRMT1) is a key regulator of renal insufficiency. In the present study, we explored the potential involvement of PRMT1 in SI‐AKI. A murine model of SI‐AKI was ind...

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Detalles Bibliográficos
Autores principales: Zhu, Yu, Wang, Longmei, Liu, Rui, Ding, Xiurong, Yin, Song, Chen, Yuankun, Zhu, Chuanlong, Wang, Zheng, Li, Wenting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549220/
https://www.ncbi.nlm.nih.gov/pubmed/37525933
http://dx.doi.org/10.1002/2211-5463.13684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549220/
https://www.ncbi.nlm.nih.gov/pubmed/37525933
http://dx.doi.org/10.1002/2211-5463.13684

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