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CDK8 and CDK19 act redundantly to control the CFTR pathway in the intestinal epithelium

CDK8 and CDK19 form a conserved cyclin‐dependent kinase subfamily that interacts with the essential transcription complex, Mediator, and also phosphorylates the C‐terminal domain of RNA polymerase II. Cells lacking either CDK8 or CDK19 are viable and have limited transcriptional alterations, but whe...

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Detalles Bibliográficos
Autores principales: Prieto, Susana, Dubra, Geronimo, Camasses, Alain, Aznar, Ana Bella, Begon‐Pescia, Christina, Simboeck, Elisabeth, Pirot, Nelly, Gerbe, François, Angevin, Lucie, Jay, Philippe, Krasinska, Liliana, Fisher, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549226/
https://www.ncbi.nlm.nih.gov/pubmed/36545778
http://dx.doi.org/10.15252/embr.202154261