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Bind&Bite: covalently stabilized heterodimeric coiled-coil peptides for the site-selective, cysteine-free chemical modification of proteins

Ensuring site-selectivity in covalent chemical modification of proteins is one of the major challenges in chemical biology and related biomedical disciplines. Most current strategies either utilize the selectivity of proteases, or are based on reactions involving the thiol groups of cysteine residue...

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Detalles Bibliográficos
Autores principales: Beutel, Jannis, Tannig, Pierre, Di Vincenzo, Riccardo, Schumacher, Thomas, Überla, Klaus, Eichler, Jutta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549240/
https://www.ncbi.nlm.nih.gov/pubmed/37799587
http://dx.doi.org/10.1039/d3cb00122a