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Arginine methylation of RNA-binding proteins is impaired in Huntington’s disease

Huntington’s disease (HD) is a progressive neurodegenerative disorder caused by a CAG repeat expansion in the HD gene, coding for huntingtin protein (HTT). Mechanisms of HD cellular pathogenesis remain undefined and likely involve disruptions in many cellular processes and functions presumably media...

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Detalles Bibliográficos
Autores principales: Ratovitski, Tamara, Kamath, Siddhi V, O'Meally, Robert N, Gosala, Keerthana, Holland, Chloe D, Jiang, Mali, Cole, Robert N, Ross, Christopher A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549789/
https://www.ncbi.nlm.nih.gov/pubmed/37535888
http://dx.doi.org/10.1093/hmg/ddad125