L-glutamic acid-g-poly hydroxyethyl methacrylate nanoparticles: acute and sub-acute toxicity and biodistribution potential in mice

The aim of this safety study in mice was to determine in vivo toxicity and biodistribution potential of a single and multiple doses of L-glutamic acid-g-p(HEMA) polymeric nanoparticles as a drug delivery system. The single dose did not cause any lethal effect, and its acute oral LD(50) was >2.000...

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Detalles Bibliográficos
Autores principales: Bakan, Buket, Oltulu, Fatih, Yıldırım, Yeliz, Yavaşoğlu, Altuğ, Akgöl, Sinan, Karabay Yavaşoğlu, Nefise Ülkü
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549881/
https://www.ncbi.nlm.nih.gov/pubmed/37791671
http://dx.doi.org/10.2478/aiht-2023-74-3768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549881/
https://www.ncbi.nlm.nih.gov/pubmed/37791671
http://dx.doi.org/10.2478/aiht-2023-74-3768

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