Non-canonical functions of a mutant TSC2 protein in mitotic division

Tuberous Sclerosis Complex (TSC) is a debilitating developmental disorder characterized by a variety of clinical manifestations. TSC is caused by mutations in the TSC1 or TSC2 genes, which encode the hamartin/tuberin proteins respectively. These proteins function as a heterodimer that negatively reg...

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Detalles Bibliográficos
Autores principales: Chalkley, Mary-Bronwen L., Mersfelder, Rachel B., Sundberg, Maria, Armstrong, Laura C., Sahin, Mustafa, Ihrie, Rebecca A., Ess, Kevin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550124/
https://www.ncbi.nlm.nih.gov/pubmed/37792789
http://dx.doi.org/10.1371/journal.pone.0292086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550124/
https://www.ncbi.nlm.nih.gov/pubmed/37792789
http://dx.doi.org/10.1371/journal.pone.0292086

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