Binding of herpesvirus entry mediator (HVEM) and HSV-1 gD affect reactivation but not latency levels

Previously we reported that the HSV-1 latency associated transcript (LAT) specifically upregulates the cellular herpesvirus entry mediator (HVEM) but no other known HSV-1 receptors. HSV-1 glycoprotein D (gD) binds to HVEM but the effect of this interaction on latency-reactivation is not known. We fo...

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Detalles Bibliográficos
Autores principales: Jaggi, Ujjaldeep, Wang, Shaohui, Mott, Kevin R., Ghiasi, Homayon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550154/
https://www.ncbi.nlm.nih.gov/pubmed/37738264
http://dx.doi.org/10.1371/journal.ppat.1011693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550154/
https://www.ncbi.nlm.nih.gov/pubmed/37738264
http://dx.doi.org/10.1371/journal.ppat.1011693

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