Live-cell imaging uncovers the relationship between histone acetylation, transcription initiation, and nucleosome mobility

Histone acetylation and RNA polymerase II phosphorylation are associated with transcriptionally active chromatin, but their spatiotemporal relationship in live cells remains poorly understood. To address this problem, we combine Fab-based labeling of endogenous protein modifications with single-mole...

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Detalles Bibliográficos
Autores principales: Saxton, Matthew N., Morisaki, Tatsuya, Krapf, Diego, Kimura, Hiroshi, Stasevich, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550241/
https://www.ncbi.nlm.nih.gov/pubmed/37792937
http://dx.doi.org/10.1126/sciadv.adh4819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550241/
https://www.ncbi.nlm.nih.gov/pubmed/37792937
http://dx.doi.org/10.1126/sciadv.adh4819

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