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Live-cell imaging uncovers the relationship between histone acetylation, transcription initiation, and nucleosome mobility
Histone acetylation and RNA polymerase II phosphorylation are associated with transcriptionally active chromatin, but their spatiotemporal relationship in live cells remains poorly understood. To address this problem, we combine Fab-based labeling of endogenous protein modifications with single-mole...
Autores principales: | Saxton, Matthew N., Morisaki, Tatsuya, Krapf, Diego, Kimura, Hiroshi, Stasevich, Timothy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550241/ https://www.ncbi.nlm.nih.gov/pubmed/37792937 http://dx.doi.org/10.1126/sciadv.adh4819 |
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