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Influence of proton pump inhibitors on the pathological response of rectal cancer: a multicentre study

BACKGROUND: The standard neoadjuvant therapy for rectal cancer involves fluoropyrimidines and radiotherapy and, most recently, total neoadjuvant therapy (TNT). A drug–drug interaction between fluoropyrimidines and proton-pump inhibitors (PPI) was suggested, with a negative impact on oncological outc...

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Detalles Bibliográficos
Autores principales: Cesca, Marcelle G, Ruiz-Garcia, Erika, Weschenfelder, Rui, D’Agustini, Nathalia, Iseas, Soledad, Luca, Romina, O’Connor, Juan Manuel, D’Alpino, Renata, Pereira, Allan A, Mello, Celso A, Aguiar, Samuel, e Silva, Virgílio Souza, Riechelmann, Rachel P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550299/
https://www.ncbi.nlm.nih.gov/pubmed/37799958
http://dx.doi.org/10.3332/ecancer.2023.1586