Leveraging osteoclast genetic regulatory data to identify genes with a role in osteoarthritis

There has been a growing interest in the role of the subchondral bone and its resident osteoclasts in the progression of osteoarthritis (OA). A recent genome-wide association study (GWAS) identified 100 independent association signals for OA traits. Most of these signals are led by noncoding variant...

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Detalles Bibliográficos
Autores principales: Mullin, Benjamin H, Zhu, Kun, Brown, Suzanne J, Mullin, Shelby, Dudbridge, Frank, Pavlos, Nathan J, Richards, J Brent, Grundberg, Elin, Bell, Jordana T, Zeggini, Eleftheria, Walsh, John P, Xu, Jiake, Wilson, Scott G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550309/
https://www.ncbi.nlm.nih.gov/pubmed/37579195
http://dx.doi.org/10.1093/genetics/iyad150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550309/
https://www.ncbi.nlm.nih.gov/pubmed/37579195
http://dx.doi.org/10.1093/genetics/iyad150

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