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Mitochondrial superoxide dismutase Sod2 suppresses nuclear genome instability during oxidative stress
Oxidative stress can damage DNA and thereby contribute to genome instability. To avoid an imbalance or overaccumulation of reactive oxygen species (ROS), cells are equipped with antioxidant enzymes that scavenge excess ROS. Cells lacking the RecQ-family DNA helicase Sgs1, which contributes to homolo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550321/ https://www.ncbi.nlm.nih.gov/pubmed/37638880 http://dx.doi.org/10.1093/genetics/iyad147 |