Cargando…

Mitochondrial superoxide dismutase Sod2 suppresses nuclear genome instability during oxidative stress

Oxidative stress can damage DNA and thereby contribute to genome instability. To avoid an imbalance or overaccumulation of reactive oxygen species (ROS), cells are equipped with antioxidant enzymes that scavenge excess ROS. Cells lacking the RecQ-family DNA helicase Sgs1, which contributes to homolo...

Descripción completa

Detalles Bibliográficos
Autores principales: Gupta, Sonia Vidushi, Campos, Lillian, Schmidt, Kristina Hildegard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550321/
https://www.ncbi.nlm.nih.gov/pubmed/37638880
http://dx.doi.org/10.1093/genetics/iyad147