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mNSCs overexpressing Rimkla transplantation facilitates cognitive recovery in a mouse model of traumatic brain injury

N-acetyl aspartyl-glutamate (NAAG) is easily inactivated for the hydrolysis of NAAG peptidase on the surface of glial cells, thereby losing its endogenous neuroprotective effect after traumatic brain injury. In this study, lentiviral vectors were used to over express/knock out NAAG synthetase II (Ri...

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Detalles Bibliográficos
Autores principales: Ji, Tongjie, Pang, Ying, Cheng, Meng, Wang, Rui, Chen, Xu, Zhang, Chunyu, Liu, Min, Zhang, Jing, Zhong, Chunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550729/
https://www.ncbi.nlm.nih.gov/pubmed/37810220
http://dx.doi.org/10.1016/j.isci.2023.107913