Identifying essential long non-coding RNAs in cancer using CRISPRi-based dropout screens

Long non-coding RNAs (lncRNAs) are emerging as key regulators in the initiation, growth, and progression of cancer. High-throughput CRISPR-based techniques systematically assess the function of genes or regulatory elements present in the human genome. Here, we present a protocol for identifying esse...

Descripción completa

Detalles Bibliográficos
Autores principales: Bril, Oscar, Schwarzmueller, Laura J., Moreno, Leandro F., Vermeulen, Louis, Léveillé, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550846/
https://www.ncbi.nlm.nih.gov/pubmed/37773752
http://dx.doi.org/10.1016/j.xpro.2023.102588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550846/
https://www.ncbi.nlm.nih.gov/pubmed/37773752
http://dx.doi.org/10.1016/j.xpro.2023.102588

Ejemplares similares