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Identifying essential long non-coding RNAs in cancer using CRISPRi-based dropout screens

Long non-coding RNAs (lncRNAs) are emerging as key regulators in the initiation, growth, and progression of cancer. High-throughput CRISPR-based techniques systematically assess the function of genes or regulatory elements present in the human genome. Here, we present a protocol for identifying esse...

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Detalles Bibliográficos
Autores principales:	Bril, Oscar, Schwarzmueller, Laura J., Moreno, Leandro F., Vermeulen, Louis, Léveillé, Nicolas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550846/ https://www.ncbi.nlm.nih.gov/pubmed/37773752 http://dx.doi.org/10.1016/j.xpro.2023.102588

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