Application of a 3D hydrogel-based model to replace use of animals for passaging patient-derived xenografts

PURPOSE: This 3D in vitro cancer model for propagation of patient-derived cells, using a synthetic self-assembling peptide gel, allows the formation of a fully characterised, tailorable tumour microenvironment. Unlike many existing 3D cancer models, the peptide gel is inert, apart from molecules and...

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Detalles Bibliográficos
Autores principales: Jones, Sal, Ashworth, Jennifer C., Meakin, Marian, Collier, Pamela, Probert, Catherine, Ritchie, Alison A., Merry, Catherine L. R., Grabowska, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550889/
https://www.ncbi.nlm.nih.gov/pubmed/37808200
http://dx.doi.org/10.1007/s44164-023-00048-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550889/
https://www.ncbi.nlm.nih.gov/pubmed/37808200
http://dx.doi.org/10.1007/s44164-023-00048-x

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