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Application of a 3D hydrogel-based model to replace use of animals for passaging patient-derived xenografts
PURPOSE: This 3D in vitro cancer model for propagation of patient-derived cells, using a synthetic self-assembling peptide gel, allows the formation of a fully characterised, tailorable tumour microenvironment. Unlike many existing 3D cancer models, the peptide gel is inert, apart from molecules and...
Autores principales: | Jones, Sal, Ashworth, Jennifer C., Meakin, Marian, Collier, Pamela, Probert, Catherine, Ritchie, Alison A., Merry, Catherine L. R., Grabowska, Anna M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550889/ https://www.ncbi.nlm.nih.gov/pubmed/37808200 http://dx.doi.org/10.1007/s44164-023-00048-x |
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