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Genotype-stratified treatment for monogenic insulin resistance: a systematic review

BACKGROUND: Monogenic insulin resistance (IR) includes lipodystrophy and disorders of insulin signalling. We sought to assess the effects of interventions in monogenic IR, stratified by genetic aetiology. METHODS: Systematic review using PubMed, MEDLINE and Embase (1 January 1987 to 23 June 2021). S...

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Detalles Bibliográficos
Autores principales: Semple, Robert K., Patel, Kashyap A., Auh, Sungyoung, Brown, Rebecca J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550936/
https://www.ncbi.nlm.nih.gov/pubmed/37794082
http://dx.doi.org/10.1038/s43856-023-00368-9