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Structural mechanisms of the human cardiac sodium-calcium exchanger NCX1

Na(+)/Ca(2+) exchangers (NCX) transport Ca(2+) in or out of cells in exchange for Na(+). They are ubiquitously expressed and play an essential role in maintaining cytosolic Ca(2+) homeostasis. Although extensively studied, little is known about the global structural arrangement of eukaryotic NCXs an...

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Detalles Bibliográficos
Autores principales: Xue, Jing, Zeng, Weizhong, Han, Yan, John, Scott, Ottolia, Michela, Jiang, Youxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550945/
https://www.ncbi.nlm.nih.gov/pubmed/37794011
http://dx.doi.org/10.1038/s41467-023-41885-4