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Genomic signatures of past and present chromosomal instability in Barrett’s esophagus and early esophageal adenocarcinoma
The progression of precancerous lesions to malignancy is often accompanied by increasing complexity of chromosomal alterations but how these alterations arise is poorly understood. Here we perform haplotype-specific analysis of chromosomal copy-number evolution in the progression of Barrett’s esopha...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550953/ https://www.ncbi.nlm.nih.gov/pubmed/37794034 http://dx.doi.org/10.1038/s41467-023-41805-6 |