Genomic signatures of past and present chromosomal instability in Barrett’s esophagus and early esophageal adenocarcinoma

The progression of precancerous lesions to malignancy is often accompanied by increasing complexity of chromosomal alterations but how these alterations arise is poorly understood. Here we perform haplotype-specific analysis of chromosomal copy-number evolution in the progression of Barrett’s esopha...

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Detalles Bibliográficos
Autores principales: Bao, Chunyang, Tourdot, Richard W., Brunette, Gregory J., Stewart, Chip, Sun, Lili, Baba, Hideo, Watanabe, Masayuki, Agoston, Agoston T., Jajoo, Kunal, Davison, Jon M., Nason, Katie S., Getz, Gad, Wang, Kenneth K., Imamura, Yu, Odze, Robert, Bass, Adam J., Stachler, Matthew D., Zhang, Cheng-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550953/
https://www.ncbi.nlm.nih.gov/pubmed/37794034
http://dx.doi.org/10.1038/s41467-023-41805-6

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