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Intermolecular interactions underlie protein/peptide phase separation irrespective of sequence and structure at crowded milieu
Liquid-liquid phase separation (LLPS) has emerged as a crucial biological phenomenon underlying the sequestration of macromolecules (such as proteins and nucleic acids) into membraneless organelles in cells. Unstructured and intrinsically disordered domains are known to facilitate multivalent intera...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550955/ https://www.ncbi.nlm.nih.gov/pubmed/37794023 http://dx.doi.org/10.1038/s41467-023-41864-9 |