Alternative splicing in lung influences COVID-19 severity and respiratory diseases

Alternative splicing generates functional diversity in isoforms, impacting immune response to infection. Here, we evaluate the causal role of alternative splicing in COVID-19 severity and susceptibility by applying two-sample Mendelian randomization to cis-splicing quantitative trait loci and the re...

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Detalles Bibliográficos
Autores principales: Nakanishi, Tomoko, Willett, Julian, Farjoun, Yossi, Allen, Richard J., Guillen-Guio, Beatriz, Adra, Darin, Zhou, Sirui, Richards, J. Brent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550956/
https://www.ncbi.nlm.nih.gov/pubmed/37794074
http://dx.doi.org/10.1038/s41467-023-41912-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550956/
https://www.ncbi.nlm.nih.gov/pubmed/37794074
http://dx.doi.org/10.1038/s41467-023-41912-4

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