Structure of the ceramide-bound SPOTS complex

Sphingolipids are structural membrane components that also function in cellular stress responses. The serine palmitoyltransferase (SPT) catalyzes the rate-limiting step in sphingolipid biogenesis. Its activity is tightly regulated through multiple binding partners, including Tsc3, Orm proteins, cera...

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Detalles Bibliográficos
Autores principales: Schäfer, Jan-Hannes, Körner, Carolin, Esch, Bianca M., Limar, Sergej, Parey, Kristian, Walter, Stefan, Januliene, Dovile, Moeller, Arne, Fröhlich, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550967/
https://www.ncbi.nlm.nih.gov/pubmed/37794019
http://dx.doi.org/10.1038/s41467-023-41747-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550967/
https://www.ncbi.nlm.nih.gov/pubmed/37794019
http://dx.doi.org/10.1038/s41467-023-41747-z

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