Cargando…

Structure of the ceramide-bound SPOTS complex

Sphingolipids are structural membrane components that also function in cellular stress responses. The serine palmitoyltransferase (SPT) catalyzes the rate-limiting step in sphingolipid biogenesis. Its activity is tightly regulated through multiple binding partners, including Tsc3, Orm proteins, cera...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schäfer, Jan-Hannes, Körner, Carolin, Esch, Bianca M., Limar, Sergej, Parey, Kristian, Walter, Stefan, Januliene, Dovile, Moeller, Arne, Fröhlich, Florian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550967/ https://www.ncbi.nlm.nih.gov/pubmed/37794019 http://dx.doi.org/10.1038/s41467-023-41747-z

Ejemplares similares

Yeast Svf1 binds ceramides and contributes to sphingolipid metabolism at the ER cis-Golgi interface
por: Limar, Sergej, et al.
Publicado: (2023)

The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells
por: Galazzo, Laura, et al.
Publicado: (2022)

Uptake of exogenous serine is important to maintain sphingolipid homeostasis in Saccharomyces cerevisiae
por: Esch, Bianca M., et al.
Publicado: (2020)

Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery
por: Shvarev, Dmitry, et al.
Publicado: (2022)

Structure of Merkel Cell Polyomavirus Capsid and Interaction with Its Glycosaminoglycan Attachment Receptor
por: Bayer, Niklas J., et al.
Publicado: (2020)

Mechanisms of Nonvesicular Ceramide Transport
por: Clausmeyer, Lena, et al.
Publicado: (2023)

Conformation space of a heterodimeric ABC exporter under turnover conditions
por: Hofmann, Susanne, et al.
Publicado: (2019)

The Role of Ceramides in Diabetes and Cardiovascular Disease Regulation of Ceramides by Adipokines
por: Field, Bianca C., et al.
Publicado: (2020)

Determining the structure of protein-bound ceramides, essential lipids for skin barrier function
por: Ohno, Yusuke, et al.
Publicado: (2023)

Antibacterial activity of ceramide and ceramide analogs against pathogenic Neisseria
por: Becam, Jérôme, et al.
Publicado: (2017)

Ceramide and ceramide 1-phosphate in health and disease
por: Arana, Lide, et al.
Publicado: (2010)

Intracellular trafficking of ceramide by ceramide transfer protein
por: Hanada, Kentaro
Publicado: (2010)

Influence of calcium on ceramide-1-phosphate monolayers
por: Oliveira, Joana S L, et al.
Publicado: (2016)

Necroptosis in primate luteolysis: a role for ceramide
por: Bagnjuk, Konstantin, et al.
Publicado: (2019)

A lysosomal biogenesis map reveals the cargo spectrum of yeast vacuolar protein targeting pathways
por: Eising, Sebastian, et al.
Publicado: (2022)

Visualization of Ceramide-Associated Proteins in Ceramide-Rich Platforms Using a Cross-Linkable Ceramide Analog and Proximity Ligation Assays With Anti-ceramide Antibody
por: Jiang, Xue, et al.
Publicado: (2019)

Ceramide in the prostate
por: Dent, Paul
Publicado: (2013)

Activation of neutral sphingomyelinase 2 through hyperglycemia contributes to endothelial apoptosis via vesicle-bound intercellular transfer of ceramides
por: Zietzer, Andreas, et al.
Publicado: (2021)

Structure of the metazoan Rab7 GEF complex Mon1–Ccz1–Bulli
por: Herrmann, Eric, et al.
Publicado: (2023)

Ceramides and Ceramide Scores: Clinical Applications for Cardiometabolic Risk Stratification
por: Hilvo, Mika, et al.
Publicado: (2020)

Imaging Mass Spectrometry Visualizes Ceramides and the Pathogenesis of Dorfman-Chanarin Syndrome Due to Ceramide Metabolic Abnormality in the Skin
por: Goto-Inoue, Naoko, et al.
Publicado: (2012)

Implication of Ceramide, Ceramide 1-Phosphate and Sphingosine 1-Phosphate in Tumorigenesis
por: Gangoiti, Patricia, et al.
Publicado: (2008)

Chemotherapy with ceramide in TNBC
por: Legembre, Patrick, et al.
Publicado: (2015)

Ceramides in Adipose Tissue
por: Li, Ying, et al.
Publicado: (2020)

Ceramide in Stress Response
por: Nikolova-Karakashian, Mariana N., et al.
Publicado: (2010)

Ceramide in cerebrovascular diseases
por: Yuan, Huiqi, et al.
Publicado: (2023)

A tissue‐specific screen of ceramide expression in aged mice identifies ceramide synthase‐1 and ceramide synthase‐5 as potential regulators of fiber size and strength in skeletal muscle
por: Tosetti, Bettina, et al.
Publicado: (2019)

Complexation of C6-Ceramide with Cholesteryl Phosphocholine – A Potent Solvent-Free Ceramide Delivery Formulation for Cells in Culture
por: Sukumaran, Pramod, et al.
Publicado: (2013)

Ceramide Synthases Expression and Role of Ceramide Synthase-2 in the Lung: Insight from Human Lung Cells and Mouse Models
por: Petrache, Irina, et al.
Publicado: (2013)

Linoleate-enriched diet increases both linoleic acid esterified to omega hydroxy very long chain fatty acids and free ceramides of canine stratum corneum without effect on protein-bound ceramides and skin barrier function
por: Popa, Iuliana, et al.
Publicado: (2018)

Horse-Derived Ceramide Accentuates Glucosylceramide Synthase and Ceramide Synthase 3 by Activating PPARβ/δ and/or PPARγ to Stimulate Ceramide Synthesis
por: Igarashi, Tami, et al.
Publicado: (2023)

Activation of Sphingomyelin Phosphodiesterase 3 in Liver Regeneration Impedes the Progression of Colorectal Cancer Liver Metastasis Via Exosome-Bound Intercellular Transfer of Ceramides
por: Li, Qingping, et al.
Publicado: (2023)

Fracture Statistics for Inorganically-Bound Core Materials
por: Lechner, Philipp, et al.
Publicado: (2018)

On the spot immunocapture in targeted biomarker analysis using paper-bound streptavidin as anchor for biotinylated antibodies
por: Johannsen, Christina, et al.
Publicado: (2022)

Ceramide and Ischemia/Reperfusion Injury
por: He, Xingxuan, et al.
Publicado: (2018)

Strong Heart, Low Ceramides
por: Holland, William L., et al.
Publicado: (2018)

Implication of Ceramide Kinase in Adipogenesis
por: Ordoñez, Marta, et al.
Publicado: (2017)

Ceramide and Regulation of Vascular Tone
por: Cogolludo, Angel, et al.
Publicado: (2019)

The Role of Ceramides in Insulin Resistance
por: Sokolowska, Emilia, et al.
Publicado: (2019)

Ceramides and Cell Signaling Molecules in Psoriatic Epidermis: Reduced Levels of Ceramides, PKC-α, and JNK
por: Lew, Bark-Lynn, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_so0qim4ac8e0cpdlkjidfkohgf