Cargando…

PACS-2 deficiency aggravates tubular injury in diabetic kidney disease by inhibiting ER-phagy

Autophagy of endoplasmic reticulum (ER-phagy) selectively removes damaged ER through autophagy-lysosome pathway, acting as an adaptive mechanism to alleviate ER stress and restore ER homeostasis. However, the role and precise mechanism of ER-phagy in tubular injury of diabetic kidney disease (DKD) r...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Jinfei, Li, Li, Li, Chenrui, Chen, Wei, Liu, Yan, Luo, Shilu, Zhao, Chanyue, Han, Yachun, Yang, Ming, Zhao, Hao, Jiang, Na, Xi, Yiyun, Tang, Chengyuan, Cai, Juan, Xiao, Li, Liu, Huafeng, Sun, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550977/
https://www.ncbi.nlm.nih.gov/pubmed/37794057
http://dx.doi.org/10.1038/s41419-023-06175-3