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PACS-2 deficiency aggravates tubular injury in diabetic kidney disease by inhibiting ER-phagy
Autophagy of endoplasmic reticulum (ER-phagy) selectively removes damaged ER through autophagy-lysosome pathway, acting as an adaptive mechanism to alleviate ER stress and restore ER homeostasis. However, the role and precise mechanism of ER-phagy in tubular injury of diabetic kidney disease (DKD) r...
Autores principales: | Yang, Jinfei, Li, Li, Li, Chenrui, Chen, Wei, Liu, Yan, Luo, Shilu, Zhao, Chanyue, Han, Yachun, Yang, Ming, Zhao, Hao, Jiang, Na, Xi, Yiyun, Tang, Chengyuan, Cai, Juan, Xiao, Li, Liu, Huafeng, Sun, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550977/ https://www.ncbi.nlm.nih.gov/pubmed/37794057 http://dx.doi.org/10.1038/s41419-023-06175-3 |
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