Disease pathology signatures in a mouse model of Mucopolysaccharidosis type IIIB

Mucopolysaccharidosis type IIIB (MPS IIIB) is a rare and devastating childhood-onset lysosomal storage disease caused by complete loss of function of the lysosomal hydrolase α-N-acetylglucosaminidase. The lack of functional enzyme in MPS IIIB patients leads to the progressive accumulation of heparan...

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Detalles Bibliográficos
Autores principales: Petrova, Ralitsa, Patil, Abhijeet R., Trinh, Vivian, McElroy, Kathryn E., Bhakta, Minoti, Tien, Jason, Wilson, David S., Warren, Liling, Stratton, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550979/
https://www.ncbi.nlm.nih.gov/pubmed/37794029
http://dx.doi.org/10.1038/s41598-023-42431-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550979/
https://www.ncbi.nlm.nih.gov/pubmed/37794029
http://dx.doi.org/10.1038/s41598-023-42431-4

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