MYL3 protects chondrocytes from senescence by inhibiting clathrin-mediated endocytosis and activating of Notch signaling

As the unique cell type in articular cartilage, chondrocyte senescence is a crucial cellular event contributing to osteoarthritis development. Here we show that clathrin-mediated endocytosis and activation of Notch signaling promotes chondrocyte senescence and osteoarthritis development, which is ne...

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Detalles Bibliográficos
Autores principales: Cao, He, Yang, Panpan, Liu, Jia, Shao, Yan, Li, Honghao, Lai, Pinglin, Wang, Hong, Liu, Anling, Guo, Bin, Tang, Yujin, Bai, Xiaochun, Li, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550997/
https://www.ncbi.nlm.nih.gov/pubmed/37794006
http://dx.doi.org/10.1038/s41467-023-41858-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550997/
https://www.ncbi.nlm.nih.gov/pubmed/37794006
http://dx.doi.org/10.1038/s41467-023-41858-7

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