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A thermostable type I-B CRISPR-Cas system for orthogonal and multiplexed genetic engineering
Thermophilic cell factories have remarkably broad potential for industrial applications, but are limited by a lack of genetic manipulation tools and recalcitrance to transformation. Here, we identify a thermophilic type I-B CRISPR-Cas system from Parageobacillus thermoglucosidasius and find it displ...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551041/ https://www.ncbi.nlm.nih.gov/pubmed/37794017 http://dx.doi.org/10.1038/s41467-023-41973-5 |