A thermostable type I-B CRISPR-Cas system for orthogonal and multiplexed genetic engineering

Thermophilic cell factories have remarkably broad potential for industrial applications, but are limited by a lack of genetic manipulation tools and recalcitrance to transformation. Here, we identify a thermophilic type I-B CRISPR-Cas system from Parageobacillus thermoglucosidasius and find it displ...

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Detalles Bibliográficos
Autores principales: Yang, Zhiheng, Li, Zilong, Li, Bixiao, Bu, Ruihong, Tan, Gao-Yi, Wang, Zhengduo, Yan, Hao, Xin, Zhenguo, Zhang, Guojian, Li, Ming, Xiang, Hua, Zhang, Lixin, Wang, Weishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551041/
https://www.ncbi.nlm.nih.gov/pubmed/37794017
http://dx.doi.org/10.1038/s41467-023-41973-5

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