Matrix stiffness regulates tumor cell intravasation through expression and ESRP1-mediated alternative splicing of MENA

During intravasation, cancer cells cross the endothelial barrier and enter the circulation. Extracellular matrix stiffening has been correlated with tumor metastatic potential; however, little is known about the effects of matrix stiffness on intravasation. Here, we utilize in vitro systems, a mouse...

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Detalles Bibliográficos
Autores principales: Wang, Wenjun, Taufalele, Paul V., Millet, Martial, Homsy, Kevin, Smart, Kyra, Berestesky, Emily D., Schunk, Curtis T., Rowe, Matthew M., Bordeleau, Francois, Reinhart-King, Cynthia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551051/
https://www.ncbi.nlm.nih.gov/pubmed/37027295
http://dx.doi.org/10.1016/j.celrep.2023.112338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551051/
https://www.ncbi.nlm.nih.gov/pubmed/37027295
http://dx.doi.org/10.1016/j.celrep.2023.112338

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