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Electrophysiological basis of cardiac arrhythmia in a mouse model of myotonic dystrophy type 1

Introduction: Myotonic dystrophy type 1 (DM1) is a multisystemic genetic disorder caused by the increased number of CTG repeats in 3′ UTR of Dystrophia Myotonia Protein Kinase (DMPK) gene. DM1 patients experience conduction abnormalities as well as atrial and ventricular arrhythmias with increased s...

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Detalles Bibliográficos
Autores principales: Ginjupalli, Vamsi Krishna Murthy, Cupelli, Michael, Reisqs, Jean-Baptiste, Sleiman, Yvonne, El-Sherif, Nabil, Gourdon, Genevieve, Puymirat, Jack, Chahine, Mohamed, Boutjdir, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551179/
https://www.ncbi.nlm.nih.gov/pubmed/37811496
http://dx.doi.org/10.3389/fphys.2023.1257682