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Profiling mitochondrial DNA mutations in tumors and circulating extracellular vesicles of triple‐negative breast cancer patients for potential biomarker development

Early detection and recurrence prediction are challenging in triple‐negative breast cancer (TNBC) patients. We aimed to develop mitochondrial DNA (mtDNA)‐based liquid biomarkers to improve TNBC management. Mitochondrial genome (MG) enrichment and next‐generation sequencing mapped the entire MG in 73...

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Detalles Bibliográficos
Autores principales: Vikramdeo, Kunwar Somesh, Anand, Shashi, Sudan, Sarabjeet Kour, Pramanik, Paramahansa, Singh, Seema, Godwin, Andrew K., Singh, Ajay Pratap, Dasgupta, Santanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551276/
https://www.ncbi.nlm.nih.gov/pubmed/37810173
http://dx.doi.org/10.1096/fba.2023-00070