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Involvement of the spinal γ-aminobutyric acid receptor in the analgesic effects of intrathecally injected hypertonic saline in spinal nerve-ligated rats

BACKGROUND: Hypertonic saline is used for treating chronic pain; however, clinical studies that aid in optimizing therapeutic protocols are lacking. We aimed to determine the concentration of intrathecally injected hypertonic saline at which the effect reaches its peak as well as the underlying γ-am...

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Detalles Bibliográficos
Autores principales: Karm, Myong-Hwan, Kwon, Hyun-Jung, Shin, Euiyong, Bae, Honggyoon, Kim, Young Ki, Choi, Seong-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551396/
https://www.ncbi.nlm.nih.gov/pubmed/37722756
http://dx.doi.org/10.3344/kjp.23162