IL-21/23 axis modulates inflammatory cytokines and RANKL expression in RA CD4(+) T cells via p-Akt1 signaling

INTRODUCTION: CD4(+) T cells are critically involved in the pathogenesis of Rheumatoid Arthritis; an autoimmune disorder characterized by joint inflammation and bone degeneration. In this study, we focused on the critical role of cytokines, IL-21 and IL-23 in facilitating the aberrant status of RA T...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Gargee, Sengupta, Soumya, Jha, Rohila, Shaw, Shubham K., Jogdand, Gajendra M., Barik, Prakash K., Padhan, Prasanta, Parida, Jyoti R., Devadas, Satish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551441/
https://www.ncbi.nlm.nih.gov/pubmed/37809066
http://dx.doi.org/10.3389/fimmu.2023.1235514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551441/
https://www.ncbi.nlm.nih.gov/pubmed/37809066
http://dx.doi.org/10.3389/fimmu.2023.1235514

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