Piperlongumine is a ligand for the orphan nuclear receptor 4A1 (NR4A1)

Piperlongumine and derivatives are being developed as anticancer agents which act primarily as inducers of reactive oxygen species (ROS) in cancer cell lines. Many of the anticancer activities of piperlongumine resemble those observed for bis-indole derived compounds that bind the orphan nuclear rec...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Martin, Greg, Mohankumar, Kumaravel, Wright, Gus A., Mariyam, Fuada, Safe, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551445/
https://www.ncbi.nlm.nih.gov/pubmed/37808182
http://dx.doi.org/10.3389/fphar.2023.1223153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551445/
https://www.ncbi.nlm.nih.gov/pubmed/37808182
http://dx.doi.org/10.3389/fphar.2023.1223153

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