Cargando…
Piperlongumine is a ligand for the orphan nuclear receptor 4A1 (NR4A1)
Piperlongumine and derivatives are being developed as anticancer agents which act primarily as inducers of reactive oxygen species (ROS) in cancer cell lines. Many of the anticancer activities of piperlongumine resemble those observed for bis-indole derived compounds that bind the orphan nuclear rec...
Autores principales: | Zhang, Lei, Martin, Greg, Mohankumar, Kumaravel, Wright, Gus A., Mariyam, Fuada, Safe, Stephen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551445/ https://www.ncbi.nlm.nih.gov/pubmed/37808182 http://dx.doi.org/10.3389/fphar.2023.1223153 |
Ejemplares similares
-
Flavone and Hydroxyflavones Are Ligands That Bind the Orphan Nuclear Receptor 4A1 (NR4A1)
por: Lee, Miok, et al.
Publicado: (2023) -
Flavonoids kaempferol and quercetin are nuclear receptor 4A1 (NR4A1, Nur77) ligands and inhibit rhabdomyosarcoma cell and tumor growth
por: Shrestha, Rupesh, et al.
Publicado: (2021) -
NR4A1 Ligands as Potent Inhibitors of Breast Cancer Cell and Tumor Growth
por: Karki, Keshav, et al.
Publicado: (2021) -
Targeting Orphan Nuclear Receptors NR4As for Energy Homeostasis and Diabetes
por: Zhang, Chenyang, et al.
Publicado: (2020) -
In Silico Adoption of an Orphan Nuclear Receptor NR4A1
por: Lanig, Harald, et al.
Publicado: (2015)