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Double trouble for prostate cancer: synergistic action of AR blockade and PARPi in non-HRR mutated patients
Prostate cancer (PCa) is the most common cancer in men worldwide. Despite better and more intensive treatment options in earlier disease stages, a large subset of patients still progress to metastatic castration-resistant PCa (mCRPC). Recently, poly-(ADP-ribose)-polymerase (PARP)-inhibitors have bee...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551452/ https://www.ncbi.nlm.nih.gov/pubmed/37810962 http://dx.doi.org/10.3389/fonc.2023.1265812 |