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Optimization of small molecule degraders and antagonists for targeting estrogen receptor based on breast cancer: current status and future

The estrogen receptor (ER) is a classical receptor protein that plays a crucial role in mediating multiple signaling pathways in various target organs. It has been shown that ER-targeting therapies inhibit breast cancer cell proliferation, enhance neuronal protection, and promote osteoclast formatio...

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Detalles Bibliográficos
Autores principales: Yao, Jiaqi, Tao, Yiran, Hu, Zelin, Li, Junjie, Xue, Ziyi, Zhang, Ya, Lei, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551544/
https://www.ncbi.nlm.nih.gov/pubmed/37808197
http://dx.doi.org/10.3389/fphar.2023.1225951