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Extensive analysis of 59 sarcoma‐related fusion genes identified pazopanib as a potential inhibitor to COL1A1‐PDGFB fusion gene

Sarcomas are malignant mesenchymal tumors that are extremely rare and divergent. Fusion genes are involved in approximately 30% of sarcomas as driver oncogenes; however, their detailed functions are not fully understood. In this study, we determined the functional significance of 59 sarcoma‐related...

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Detalles Bibliográficos
Autores principales: Hirose, Takeshi, Ikegami, Masachika, Kojima, Shinya, Yoshida, Akihiko, Endo, Makoto, Shimada, Eijiro, Kanahori, Masaya, Oyama, Ryunosuke, Matsumoto, Yoshihiro, Nakashima, Yasuharu, Kawai, Akira, Mano, Hiroyuki, Kohsaka, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551592/
https://www.ncbi.nlm.nih.gov/pubmed/37592448
http://dx.doi.org/10.1111/cas.15915