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Targeting the loss of cGAS/STING signaling in cancer
The cGAS/STING pathway provides a key host defense mechanism by detecting the accumulation of cytoplasmic double‐stranded DNA (dsDNA) and mediating innate and adaptive immune signaling. In addition to detecting pathogen‐derived dsDNA, cGAS senses intrinsic dsDNA, such as those associated with defect...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551601/ https://www.ncbi.nlm.nih.gov/pubmed/37475576 http://dx.doi.org/10.1111/cas.15913 |