Fibroblast inhibition by tocilizumab enabled gemcitabine/nab‐paclitaxel rechallenge for pancreatic cancer

Interleukin‐6 (IL‐6)/signal transducer and activator of transcription 3 (STAT3) pathway inhibition may overcome chemoresistance of metastatic pancreatic cancer (MPC). We sought to determine the safety and recommended dose of tocilizumab (TCZ), an IL‐6 receptor monoclonal antibody, and biological cor...

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Detalles Bibliográficos
Autores principales: Mitsunaga, Shuichi, Ikeda, Masafumi, Imaoka, Hiroshi, Sasaki, Mitsuhito, Watanabe, Kazuo, Sato, Akihiro, Aoki, Kazunori, Ochiai, Atsushi, Makikawa, Mayu, Nishidate, Masanobu, Yamaguchi, Kyoko, Terao, Kimio, Sawada, Noriaki, Fujitomo, Takashi, Fujii, Etsuko, Kato, Atsuhiko, Tsunoda, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551603/
https://www.ncbi.nlm.nih.gov/pubmed/37605479
http://dx.doi.org/10.1111/cas.15929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551603/
https://www.ncbi.nlm.nih.gov/pubmed/37605479
http://dx.doi.org/10.1111/cas.15929

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