Fibroblast inhibition by tocilizumab enabled gemcitabine/nab‐paclitaxel rechallenge for pancreatic cancer

Interleukin‐6 (IL‐6)/signal transducer and activator of transcription 3 (STAT3) pathway inhibition may overcome chemoresistance of metastatic pancreatic cancer (MPC). We sought to determine the safety and recommended dose of tocilizumab (TCZ), an IL‐6 receptor monoclonal antibody, and biological cor...

Descripción completa

Detalles Bibliográficos
Autores principales: Mitsunaga, Shuichi, Ikeda, Masafumi, Imaoka, Hiroshi, Sasaki, Mitsuhito, Watanabe, Kazuo, Sato, Akihiro, Aoki, Kazunori, Ochiai, Atsushi, Makikawa, Mayu, Nishidate, Masanobu, Yamaguchi, Kyoko, Terao, Kimio, Sawada, Noriaki, Fujitomo, Takashi, Fujii, Etsuko, Kato, Atsuhiko, Tsunoda, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551603/
https://www.ncbi.nlm.nih.gov/pubmed/37605479
http://dx.doi.org/10.1111/cas.15929

Ejemplares similares

Ejemplares similares