FAM111A regulates replication origin activation and cell fitness

FAM111A is a replisome-associated protein and dominant mutations within its trypsin-like peptidase domain are linked to severe human developmental syndrome, the Kenny–Caffey syndrome. However, FAM111A functions remain unclear. Here, we show that FAM111A facilitates efficient activation of DNA replic...

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Detalles Bibliográficos
Autores principales: Rios-Szwed, Diana O, Alvarez, Vanesa, Sanchez-Pulido, Luis, Garcia-Wilson, Elisa, Jiang, Hao, Bandau, Susanne, Lamond, Angus, Alabert, Constance
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551639/
https://www.ncbi.nlm.nih.gov/pubmed/37793778
http://dx.doi.org/10.26508/lsa.202302111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551639/
https://www.ncbi.nlm.nih.gov/pubmed/37793778
http://dx.doi.org/10.26508/lsa.202302111

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