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FAM111A regulates replication origin activation and cell fitness
FAM111A is a replisome-associated protein and dominant mutations within its trypsin-like peptidase domain are linked to severe human developmental syndrome, the Kenny–Caffey syndrome. However, FAM111A functions remain unclear. Here, we show that FAM111A facilitates efficient activation of DNA replic...
Autores principales: | Rios-Szwed, Diana O, Alvarez, Vanesa, Sanchez-Pulido, Luis, Garcia-Wilson, Elisa, Jiang, Hao, Bandau, Susanne, Lamond, Angus, Alabert, Constance |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551639/ https://www.ncbi.nlm.nih.gov/pubmed/37793778 http://dx.doi.org/10.26508/lsa.202302111 |
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